Michel L Tremblay Selected Research

Insulin Receptor

11/2009	Deletion of protein tyrosine phosphatase 1b improves peripheral insulin resistance and vascular function in obese, leptin-resistant mice via reduced oxidant tone.
12/2005	Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: from diabetes, obesity to cell cycle, and cancer.

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Michel L Tremblay Research Topics

Disease

38	Neoplasms (Cancer) 03/2024 - 05/2004
12	Obesity 09/2013 - 04/2002
11	Inflammation (Inflammations) 01/2024 - 06/2008
11	Insulin Resistance 01/2015 - 02/2002
8	Breast Neoplasms (Breast Cancer) 10/2020 - 12/2009
8	Carcinogenesis 10/2020 - 02/2004
7	Neoplasm Metastasis (Metastasis) 01/2017 - 03/2007
5	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 12/2007
4	Cachexia 03/2024 - 02/2012
4	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 01/2010
4	Prostatic Neoplasms (Prostate Cancer) 01/2016 - 01/2009
4	Weight Gain 01/2015 - 04/2002
4	Body Weight (Weight, Body) 01/2015 - 01/2010
3	Arthritis (Polyarthritis) 01/2020 - 03/2012
3	Rheumatoid Arthritis 01/2019 - 03/2012
3	Metabolic Diseases (Metabolic Disease) 09/2013 - 04/2010
3	Type 2 Diabetes Mellitus (MODY) 07/2010 - 06/2008
2	Alzheimer Disease (Alzheimer's Disease) 05/2024 - 03/2011
2	Anorexia 03/2024 - 02/2012
2	Cardiomegaly (Heart Hypertrophy) 01/2022 - 02/2008
2	Hypertrophy 01/2022 - 06/2012
2	Colitis 04/2018 - 01/2010
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2015 - 12/2011
2	Nephritis 09/2014 - 05/2004
2	Hypertension (High Blood Pressure) 11/2012 - 09/2009
2	Gliosis 03/2010 - 04/2005
2	Hypersensitivity (Allergy) 01/2010 - 07/2006
2	Leishmaniasis 09/2009 - 12/2007
2	Diabetes Mellitus 09/2009 - 02/2002
2	Infections 03/2009 - 12/2007
1	Nervous System Diseases (Neurological Disorders) 01/2023
1	Acute Liver Failure (Fulminant Hepatic Failure) 11/2022
1	Kidney Neoplasms (Kidney Cancer) 07/2021
1	Colorectal Neoplasms (Colorectal Cancer) 01/2021
1	Immune System Diseases (Immune Disorders) 01/2021
1	Celiac Disease (Celiac Sprue) 01/2021
1	Lesch-Nyhan Syndrome (Choreoathetosis Self Mutilation Hyperuricemia Syndrome) 01/2021
1	Virus Diseases (Viral Diseases) 12/2020
1	COVID-19 12/2020
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 10/2017
1	Encephalomyelitis (Myeloencephalitis) 10/2017
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2017
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2016

Drug/Important Bio-Agent (IBA)

19	Protein Tyrosine PhosphatasesIBA 05/2024 - 12/2005
17	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2021 - 01/2009
15	Non-Receptor Type 2 Protein Tyrosine PhosphataseIBA 01/2021 - 05/2004
14	Proteins (Proteins, Gene)FDA Link 01/2023 - 12/2004
12	Insulin (Novolin)FDA Link 01/2015 - 02/2002
11	Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA 01/2022 - 04/2002
11	Tyrosine (L-Tyrosine)FDA Link 01/2021 - 12/2004
10	EnzymesIBA 01/2021 - 02/2004
9	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 01/2024 - 09/2009
8	CytokinesIBA 03/2024 - 12/2011
5	Biomarkers (Surrogate Marker)IBA 05/2024 - 04/2009
4	LeptinIBA 03/2012 - 04/2002
3	Hormones (Hormone)IBA 03/2024 - 04/2002
3	Messenger RNA (mRNA)IBA 03/2016 - 01/2010
3	Janus KinasesIBA 01/2016 - 09/2009
3	Glucose (Dextrose)FDA LinkGeneric 01/2015 - 11/2009
3	Class 2 Receptor-Like Protein Tyrosine PhosphatasesIBA 03/2010 - 04/2005
3	CortactinIBA 03/2009 - 06/2008
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2024 - 04/2014
2	Small Interfering RNA (siRNA)IBA 01/2021 - 12/2004
2	Phosphotransferases (Kinase)IBA 01/2021 - 01/2012
2	Peptide Hydrolases (Proteases)FDA Link 03/2016 - 03/2009
2	Androgen Receptors (Androgen Receptor)IBA 02/2014 - 03/2012
2	Leptin ReceptorsIBA 09/2013 - 11/2012
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 06/2012 - 06/2012
2	Serine (L-Serine)FDA Link 03/2011 - 07/2009
2	Interleukin-6 (Interleukin 6)IBA 08/2010 - 01/2010
2	Insulin ReceptorIBA 11/2009 - 12/2005
1	sigma Receptors (sigma Receptor)IBA 05/2024
1	Acetaminophen (Paracetamol)FDA LinkGeneric 11/2022
1	MicroRNAs (MicroRNA)IBA 01/2022
1	Propylthiouracil FDA Link 01/2022
1	Thyroid HormonesIBA 01/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 01/2022
1	Triiodothyronine (Liothyronine)FDA LinkGeneric 01/2022
1	IsotopesIBA 07/2021
1	purineIBA 01/2021
1	Janus Kinase InhibitorsIBA 12/2020
1	SARS-CoV-2 spike proteinIBA 12/2020
1	Tight Junction ProteinsIBA 11/2020
1	Adenosine Triphosphatases (ATPase)IBA 10/2020
1	Antirheumatic Agents (DMARD)IBA 01/2020
1	Tumor Necrosis Factor InhibitorsIBA 01/2020
1	Dextrans (Dextran)FDA Link 04/2018
1	SodiumIBA 04/2018
1	Peptides (Polypeptides)IBA 10/2017
1	Interleukin-12 (IL 12)IBA 01/2017
1	Tyrosine Kinase InhibitorsIBA 12/2016
1	Lapatinib (GW572016)FDA Link 12/2016
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 12/2016
1	MagnesiumIBA 05/2016
1	Angiotensin IIIBA 03/2016

Therapy/Procedure

12	Therapeutics 03/2024 - 07/2008
3	Immunotherapy 01/2024 - 01/2017
1	Ligation 01/2024
1	Liver Transplantation 11/2022